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Click here or scroll down to respond to this candidate Candidate's Name
Street Address Village Green Blvd., Apt 202 EMAIL AVAILABLE
Ann Arbor, MI Street Address (480) 369-3365
CAREER SUMMARY
8 years of extensive experience in organic chemistry and analytical chemistry
Ph.D degree in Medicinal Chemistry (College of Pharmacy)
Received several research grants and awards with the optimization of active compounds
EDUCATION
Channom National University Gwang-ju, South Korea
Ph.D. in Pharmacy (Medicinal Chemistry), GPA: 4.38/4.50 February 2012
Stony Brook University Stony Brook, NY
M.S. in Marine and Atmospheric Sciences (Marine Chemistry), GPA: 3.02/4.00 May 2008
Pukyong National University Busan, South Korea
B.S. in Oceanography (major), Chemistry (minor), GPA: 3.90/4.50 February 2004
RESEARCH EXPERIENCE
University of Michigan Ann Arbor, MI
Visiting Assistant Research Scientist 2013-present
Extensively working on organic synthesis of novel small-molecule compounds, development of efficient
synthetic pathways, and structural modification by analysis of structure-activity relationship and docking mode
Frequent and regular operation and maintenance of analytical instruments such as HPLC-MS or NMR, and
such instruments as microwave reactor or flash purification system (Biotage Isolera)
Developed heuristics for efficient resource allocation with analysis of statistical data
Chonnam National University Gwang-ju, South Korea
Ph.D Researcher 2008-2013
Conducted synthesis of small-molecule chemical libraries and optimization of active compounds
Conducted computer-aided drug design by using FlexX or SurflexDock
Operation and maintenance of MPLC and LCMS
Stony Brook University Stony Brook, NY
Volunteer Research Assistant 2008-2008
Constructed synthesis of biologically active small-molecule compounds
Developed new efficient synthetic methods
LEADERSHIP EXPERIENCE
Chonnam National University Gwang-ju, South Korea
Teaching Assistant 2009-2012
Teaching 1 undergraduate course ranging in size from 40-50 students.
Topics included: General Chemistry Laboratory Experiments
Prepared course materials, and Supervised students during experiments, graded exams and weekly homework
Stony Brook University Stony Brook, NY
Teaching Assistant 2005-2006
Assisted in teaching 1 undergraduate courses ranging in size from 30-50 students.
Topics included: General Chemistry Laboratory Experiments
Supervised students in final projects, graded exams and weekly homework
Candidate's Name
354 Village Green Blvd., Apt 202 EMAIL AVAILABLE
Ann Arbor, MI 48105 (480) 369-3365
SKILLS
Software: ChemDraw, ChemFinder, SciFinder, MestRenova, Sybyl, Microsoft Office.
Experimental and analytical skills: Biotage Isolera, Biotage Initiator, Bruker NMR, Shimadzu HPLC-MS, Waters
HPLC.
SELECTED AWARDS AND RECOGNITIONS
Post-doc training from fostering next-generation researcher program, Grant award, National Research Foundation of
Korea 2012 & 2013
Research/Teaching Assistantship, Chonnam National University 2009-2012
Research Assistantship, Stony Brook University 2006-2007
Teaching Assistantship, Stony Brook University 2005-2006
Basic Research Promotion Fund Scholarship, Korea Research Foundation 2005-2007
SELECTED PUBLICATIONS
K. Ramkumar, S. Samanta, A. Kyani, S. Yang, S. Tamura, L. Ziemke, J. Stuckey, S. Li, K. Chinnaswamy, H. Otake, B.
Debnath, V. Yarovenko, J. Sebolt-Leopold, M. Ljungman, and N. Neamati, Mechanistic evaluation and
transcriptional signature of a Glutathione S-transferase Omega 1 inhibitor, Nature Comm., (2016), 7, 13084.
S. Yang, J. K. R., S. Lim, T. G. Choi, J.-H. Kim, S. Akter, M. Jang, H.-J. Ahn, H.-Y. Kim, M. P. Windisch, D. B.
Khadka, C. Zhao, Y. Jin, I. Kang, J. Ha, B.-C. Oh, M. Kim, S. S. Kim, W.-J. Cho, Structure-Based Discovery of
Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections, J. Med. Chem., (2015), 58 (24),
9546-9561.
S. Yang, C.-H. Song, H. T. M. Van, E. Park, D. B. Khadka, E.-Y. Gong, K. Lee, and W.-J. Cho, SAR Based Design of
Nicotinamides as a Novel Class of Androgen Receptor Antagonists for Prostate Cancer, J. Med. Chem., (2013), 56
(8), 3414-3418.
C.-H. Song, S. Yang (co-first), E. Park, S. H. Cho, Eun-Yeung Gong, D. B. Khadka, W.-J. Cho, and K. Lee,
Structure-Based Virtual Screening and Identification of a Novel AR Antagonist, J. Biol. Chem., (2012), 287 (36),
PHONE NUMBER AVAILABLE
T. N. Le, S. Yang (co-first), D. B. Khadka, S. H. Cho, C. Zhao, W.-J. Cho, Synthetic approaches to natural
antioxidant Benzastatin E, F and G analogues, Bull. Korean Chem. Soc., (2011), 32 (12), 4309-4315.
S. Yang, D. B. Khadka, S. H. Cho, H.-K. Ju, K. Y. Lee, K.-T. Lee, W.-J. Cho, Virtual screening and synthesis of
quinazolines as novel JAK2 inhibitors. Bioorg. Med. Chem., (2011), 19 (2), 968-977.
S. Yang, H. T. M. Van, T. N. Le, D. B. Khadka, S. H. Cho, K.-T. Lee, E.-S. Lee, Y. B. Lee, C.-H. Ahn, W.-J. Cho,
Development of 3-aryl-1-isoquinolinamines as potent antitumor agents based on CoMFA, Eur. J. Med. Chem.
(2010), 45 (11), 5493-5497.
S. Yang, H. T. M. Van, T. N. Le, D. B. Khadka, S. H. Cho, K.-T. Lee, H.-J. Chung, S. K. Lee, C.-H. Ahn, Y. B. Lee,
W.-J. Cho, Synthesis, in vitro and in vivo evaluation of 3-arylisoquinolinamines as potent antitumor agents, Bioorg.
Med. Chem. Lett., (2010), 20 (17), 5277-5281.
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