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At Encoded, we are combining the precision of gene regulation with the versatility of gene therapies to create breakthrough treatments for individuals living with severe genetic diseases. We focus on delivering life-changing advances for individuals with genetic disorders not addressable with current approaches. Encoded Therapeutics is funded by world-class healthcare investors Venrock, Arch Venture Partners, Illumina Ventures, and Matrix Capital Management. For more information, please visit (link removed)(link removed)>

This is a unique opportunity to work at the intersection of genomics and therapeutics and participate in the development of a diverse therapeutic pipeline driven by a transformative core technology. The position of Research Associate I/II will join the Downstream Process Development group at Encoded Therapeutics. A qualified candidate will be responsible for guided execution of purification process studies, and purification of samples supporting upstream PD. The ideal candidate will be hardworking, flexible, and able to work across multiple projects in a fast-paced and dynamic environment.

Responsibilities

• Develop and carry out bench scale unit operations for rAAV purification including chromatography, depth filtration, tangential flow-filtration, and viral filtration.
• Utilize analytical methods including SEC-HPLC, ELISA, and SDS-PAGE.
• Analyze, interpret, and present process performance and product quality data.
• At times, run purification processes at pilot scale.
• Meticulously maintain complete and accurate records of all work performed in an ELN.
• Contribute to authoring and reviewing technical reports and SOPs.
• Participate in process transfer activities

Requirements

• B.S (link removed) M.S. in a chemical engineering, biochemical engineering, biochemistry or related field
• 0-2 years of industry or academic experience in assay, purification or in a process development setting
• Effective interpersonal communication and presentation skills
• Ability to write clear and concise technical documents
• Enthusiasm to work with a team to meet shared objectives
• Proficient in Microsoft based Windows programs such as Excel, Powerpoint and Word.

Preferred Qualifications

• Industry experience in a purification process development or process troubleshooting role
• Skill with chromatography instrumentation and control software, especially kta systems and UNICORN software
• Experience with AAV purification
• Capability to perform statistical data analysis, which may include DoE, use of JMP software
• Familiarity with Empower, SoftMax Pro

The anticipated salary range for candidates who will work in California is $80,000 - $110,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, education, etc. Encoded Therapeutics is a multi-state employer and this salary range may not reflect positions that work in other states.

A hired applicant may be eligible for an annual bonus as well as equity under the companys stock plan.

Benefits

• Comprehensive benefits package, including competitive employer premium contributions
• Meaningful stock option grants
• PTO, sick time and holiday pay
• Generous Parental Leave program
• Pre-tax medical and dependent care programs
• STD, LTD, Life and AD&D
• Professional development opportunities
• Team-building events
• Fully stocked kitchen
• Purple Tie dry cleaning service
• Fitness center

Encoded is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Encoded is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. All employment decisions at Encoded are based on business needs, job requirements and individual qualifications, without regard to race, religion or belief, color, national origin, gender, status as a protected veteran, status as an individual with a disability, or any other status protected by the laws or regulations in the location in which we operate. Encoded will not tolerate discrimination or harassment based on any of these characteristics. Encoded encourages applicants of all ages.

If you need assistance or an accommodation due to a disability, you may call us at +1 650-491-0272.