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Research Associate Biochemistry Biophysics
Location:
US-MA-Cambridge
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At Foghorn Therapeutics, we believe in People First, Mission Always.

We put People First because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics demonstrated by our community speaking more than 22 languages and representing over 24 nationalities. We value our teammates as people, not just as employees validated by our actions that let our people know that we care about them, their families, and their lives.

We say Mission Always because we know a relentless commitment to our mission will make a difference in the lives of others. We believe our success will come from evaluating the data to follow the science. We work hard to develop a new class of therapies that could improve the lives of over 2.5 million people with cancer.

Our culture is focused on succeeding through the evaluation of data, not people. And in that, relationships can flourish and develop.

Our Science:

The groundbreaking science behind our therapies continues to yield vital insights into diseases that have confounded physicians and researchers. Our core scientific approach is centered on the chromatin regulatory system, which opens and closes the right sections of DNA at the right time. Breakdowns in the chromatin regulatory system lead to a wide range of diseases, including cancer, impacting millions of people.

Our proprietary Gene Traffic Control platform is a powerful tool for understanding and modulating the chromatin regulatory system. We are pursuing multiple treatments for breakdowns in this system. We are the only company with the ability to study and target the chromatin regulatory system at scale, in context, and in an integrated way.

Learn more about Foghorn at (link removed)(link removed)>

Job Summary

Foghorn is seeking a highly motivated, enthusiastic, and collaborative Research Associate to join our Drug Discovery team in a lab-based role to support early discovery projects in oncology. As a member of our Drug Discovery team the candidate will have an opportunity to employ various biochemical and biophysical assay technologies in mechanism of action studies, screening and hit validation. This is an onsite and lab based role.

Key Responsibilities

  • Design, develop and troubleshoot in vitro biochemical and biophysical assays for both protein-protein and small molecule-protein interactions
  • Profile compounds to support hit validation and lead optimization efforts
  • Analyze, interpret, and document data using an Electronic Laboratory Notebook and data analysis software tools
  • Work collaboratively as part of multidisciplinary team and present results to project teams



Requirements

Minimum Qualifications

  • BA/BS in Biochemistry, Biophysics, or related field
  • 1+ year Lab experience in academia or industry
  • 1+ year experience with fluorescence-based assay techniques

Preferred qualifications, skills, and competencies

  • MS degree in Biochemistry or Biophysics
  • 2+ years of relevant lab experience in biotechnology industry
  • 2+ years of experience with fluorescence-based assay techniques (e.g., HTRF, FP, Alpha) and label-free technologies (e.g., ITC, DSF, SPR, MST) is desired
  • Cell culture skills and experience with cell-based assays is a plus
  • Familiarity with automated liquid handling instrumentation is a plus
  • Demonstrated ability to analyze, interpret and present data in a clear manner
  • Ability to learn new techniques quickly and a focus on attention to detail
  • Excellent communication and inter-personal skills with ability to work collaboratively on cross functional teams

Benefits

Foghorn Therapeutics is pleased to provide you and your family with a comprehensive suite of benefits, including:

  • Highly competitive and inclusive medical, dental and vision coverage options
  • 401k retirement plan with company match
  • FSA and HSA for medical expenses and dependent care expenses
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Unlimited paid time off policy
  • Discretionary winter shut down
  • Generous Paid Leave offerings, including 12 weeks of 100% paid parental leave
  • Paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Free parking or subsidized commuter passes

Foghorn Therapeutics

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