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The position represents an opportunity to join the client Scientific Cell Biology R&D team responsible for identifying and developing novel technologies for incorporation into new products, generating application data and supporting marketing initiatives. The individual will execute scientific research individually and as part of cross-functional development teams to reach these goals.
What will you do?
The individual will work as part of the Cell Biology R&D team to lead projects related to viral vector production for gene therapy and develop our product pipeline within the client product commercialization process under the Gibco brand.
Cell line development (including omics analyses, cell line engineering, etc) to enhance viral vector production in mammalian cells.
Development of reagents to improve viral vector titers, quality, infectivity.
Optimize downstream process development to improve viral vector purification yields.
Design and/or optimize assays for quality assessment of viral particles.
Work in a matrix environment to conceive, design, and implement strategies to address current challenges associated with virus production and downstream characterization.
Prepare and present experimental data summaries and protocol writing.
Perform literature searches related to products under development and new idea generation.
Make contributions to scientific literature and conferences.
Comply with all company safety regulations and procedures.
Maintain accurate lab notebooks and training files in accordance with relevant client required standards to support patent application and defense as well as other international standards (e.g., ISO compliance, GLP/GMP requirements, etc.).
Education Requirements (Basic Qualifications)
Candidate will possess advanced degree in Virology Cell Biology or related discipline:
Ph.D. degree with 1-3 years industry or post-doc experience M.S. degree with 5+ years of relevant industry experience Knowledge, Skills, Abilities
In depth knowledge and extensive experience with viral vector production in mammalian cells.
Hands on experience with analytical methods for measuring titers of LV, including flowcytometry, qPCR, ddPCR, ELISA, and other relevant assays.
Experience with LV purification and downstream characterization assays Omics analyses, next generation sequencing and/or cell line engineering experience a plus.
Demonstrated competence completing tasks under direct supervision.
Solid technical writing skills.
Excellent time management skills and multi-tasking capabilities.
Excellent organizational skills.
Strong verbal and written communication skills and the ability to interpret, summarize, and present scientific results in a clear, concise, accurate manner to both technical and non-technical audiences.
Demonstrated ability to achieve results and solve problems.
Varite Inc
