Responsibilities:

• Design and execute protocols to solve process-related manufacturing investigations and drive process improvements by using laboratory and pilot scale-down models in protein chromatography, viral inactivation, viral filtration, ultrafiltration/diafiltration, membrane filtration, depth filtration, and centrifugation.


•  Document experimental data and results, verify and interpret data with respect to the laboratory protocol and manufacturing process.


•  Evaluation of new process technologies, including multicolumn continuous chromatography (MCC) operation.


•  Characterization of products and impurities.


•  Buffer preparation and column packing.


•  Appropriate GLP/GMP procedures must be followed.

Qualifications

•  MS or BS in Biochemistry, Chemical Engineering, or related field with 2–4 or 4–6 years, respectively, of relevant industrial and/or academic experience.


•  Knowledge of protein purification, protein stability, and demonstrated experimental skills for laboratory work are required.


•  Experience with AKTA purification operations and UNICORN method writing is helpful.


•  Experience with process scale-up/scale-down and process characterization is a plus.


•  Critical qualities include a high degree of initiative, good verbal and written communication skills, strong scientific skills and attention to detail, and the ability to work in a team environment.