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(Senior) Genetic Data Scientist - Statistical Geneticist
Location:
US-CA-South San Francisco
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Salary: $140,000.00

We have partnered with a large biotechnology company in the South San Francisco, CA area to provide them with a Senior Genetic Data Scientist Statistical Geneticist (REMOTE).

Please review the below description and let us know if you are interested.

Responsibilities of the Senior Genetic Data Scientist Statistical Geneticist:

  • Will lead the development of cutting-edge statistical approaches and workflows to analyze large-scale human cohorts with genetic and multi-dimensional, multi-modality phenotypic data. These will be obtained from public sources, as well as private datasets generated in-house and obtained through our collaborations.
  • Use genetic association and other statistical genetics techniques that involve integration of genetic, genomic, and clinical data to guide in vitro disease model development.
  • Work closely with a cross-functional team of life scientists, bioengineers, and machine learning scientists to integrate human level data with our high-throughput in-house in vitro genomic and phenotypic data to identify therapeutic targets and develop drugs that have high efficacy and low toxicity.
  • Requirements of the Senior Genetic Data Scientist Statistical Geneticist:

    • Ph.D. in statistics, genetics, computational biology or a related discipline, or equivalent practical experience
    • Demonstrated ability to use and develop cutting edge methods for analyzing human genetic data
    • Hands-on experience with genetic association testing (eQTL mapping, GWAS, EWAS, PheWAS, etc.) and/or post-association analysis using summary statistics (fine mapping, colocalization, LD score regression, meta-analysis, etc.)
    • Experience mining modern, large-scale genetic databases (e.g. ExAC/gnomAD, UK Biobank, UK10K, EBI GWAS Catalog, 1KG, etc.)
    • Strong fundamentals in applied multivariate statistics; experience working with statistical models for complex datasets, effectively measuring goodness of fit and estimating confidence
    • Proficiency in working with large-scale datasets in Python; experience with R, C/C++ or other compiled, statically typed languages is a plus
    • Ability to communicate effectively and collaborate with people of diverse backgrounds and job functions

    Nice to have experience for the Senior Genetic Data Scientist Statistical Geneticist:

    • Experience working with multi-dimensional phenotypes
    • Experience working with genomic data from different modalities (DNA sequencing, RNA-seq, proteomics, DNA accessibility assays, etc.)
    • Experience integrating genetic studies from diverse populations, including correcting for population structure, ethnicity or differences between genotyping platforms
    • Experience applying quantitative trait loci (QTL) approaches to clinical data, including imaging data
    • Familiarity with cloud computing services (e.g., AWS or GCP) and workflow management tools or batch scheduling systems (e.g. SLURM)
    • Proficiency in Linux environment (including shell/Bash scripting), experience with database languages (e.g., SQL) and experience with version control practices and tools (e.g. Git)

    Benefits of the Senior Genetic Data Scientist Statistical Geneticist:

    • Medical Insurance
    • Dental Insurance
    • Vision Insurance

    About Relevante, Inc. the Recruiting Firm Representing the Client for this Job

    Relevante is an accounting & technology direct hire recruiting and contract staffing firm. We help our Clients identify and recruit the best talent in the market and help our candidates win engaging and enriching jobs. Our Clients are some of the best companies to work for among F1000 and emerging fast growth companies in the region. Relevante has been consistently ranked as a fast growth company and one of the largest recruiting, accounting, and management consulting firms in the Philadelphia region. To stay connected with our network, please join one of our groups on LinkedIn http://www.linkedin.com/groups?mostPopular=&gid=2901

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